If you want to use your NetScaler for all things that need to be accessible from the outside, over a single IP address, that poses an issue. As is usually a problem with small to medium sized businesses which only have
XenApp/XenDesktop – “Please Wait For Local Session Manager” message when logging into RDS
I came upon this quite frequent issue with my XenDesktop 7.8 Hosted Shared Desktop environment based on Windows Server 2008 R2. Folder Redirection via GPO is in place, whereas Citrix User Profile Management is not used.